Endocrine disruption of oestrogen action and female reproductive tract cancers
نویسندگان
چکیده
منابع مشابه
Endocrine disruption of oestrogen action and female reproductive tract cancers.
Endocrine disrupting chemicals (EDC) are ubiquitous and persistent compounds that have the capacity to interfere with normal endocrine homoeostasis. The female reproductive tract is exquisitely sensitive to the action of sex steroids, and oestrogens play a key role in normal reproductive function. Malignancies of the female reproductive tract are the fourth most common cancer in women, with end...
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There is growing evidence of the impact of estrogenic contaminants in the environment. Studies have shown that male fish in detergent-contaminated water express female characteristics, turtles are sex-reversed by polychlorinated biphenyls (PCBs), male frogs exposed to a common herbicide form multiple ovaries, pseudohermaphroditic offspring are produced by polar bears, and seals in contaminated ...
متن کاملEffects of endocrine disruptors in the development of the female reproductive tract.
Environmental agencies have identified a growing number of environmental contaminants that have endocrine disrupting activity, and these can become a major public health problem. It is suggested that endocrine disruptors could account for the higher-than-expected increase in the prevalence of some non-communicable diseases, such as obesity, diabetes, thyroid diseases, and some cancers. Several ...
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Seventeen female patients who underwent orthotopic liver transplantation between June 1973 and June 1987 became pregnant 5 months to 11 years after transplantation. Immunosuppression was maintained with combinations of prednisone, cycloeporine, and azathioprine prior to and during pregnancy. One patient discontinued immunosuppression after knowledge of pregnancy, taking only azathioprine sporad...
متن کاملComparative female reproductive tract development and morphology
A brief description of the basic pattern of mammalian organogenesis of the female reproductive tract is presented based on events as they occur in human beings. The emphasis is not on the details of this development, but rather its organization and timing. Tables of comparative development provide a comparison of similar events between man, rat, mouse, and chick.
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ژورنال
عنوان ژورنال: Endocrine-Related Cancer
سال: 2013
ISSN: 1351-0088,1479-6821
DOI: 10.1530/erc-13-0342